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Shire has acquired the trading assets of SCM Pharma, securing the future of 80 jobs at its Northumberland-based pharmaceutical manufacturing facilities.

Shire, the Basingstoke-based pharmaceuticals company, is to be acquired by US-based AbbVie for £31bn.

Shire is to acquire Jerini, the German biotechnology company, for £260m, in order to expand its genetic therapy business.

Shire, the pharmaceuticals group, is to relocate its tax base to Ireland, but the 300 staff will remain in Basingstoke.

Shire is to sell a portfolio of dermatology products sold in the UK, France, Germany, Italy, Spain and Ireland to Almirall for £104m, in order to focus on its main biopharmaceuticals business.

Shire is to acquire New River Pharmaceuticals of the US for £1.3bn, in order to gain control of Vyvanse, a new drug for attention deficit hyperactivity disorder.

Shire is planning to acquire Transkaryotic Therapies, the US biotechnology company, for about £920m.