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Misys, the banking software firm with 4,000 staff, has accepted a £1.3bn takeover offer from Vista Equity Partners of the US.

Misys is to acquire Sophis, the Irish capital markets software supplier with 360 staff, for £375m.

Misys is to sell its US-based diagnostic information business to Vista Equity Partners for £186m and its US-based CPR health systems business to QuadraMed for £16m.

Misys has acquired SC Fino Capital, the Romanian financial software development company with 67 staff.

Misys is to sell Apollo, its French asset management business, to Atos Euronext Market Solutions for £1.6m.

Misys is to acquire Neomalogic, the French trade finance solutions provider, for £8.3m.

Misys is to acquire Intesio, the German banking software company, for £6.9m.

Misys is to acquire Payerpath, the US-based online processor of health claims, for £27m.

Misys is to acquire Almonde, the supplier of risk management software with 35 staff in London and Paris, for £10m.

Misys has acquired IQ Financial Systems, the US banking software developer, from Deutsche Bank for £24m.

Misys has sold its UK-based back office software products business to a management buy-out backed by Primary Capital, and the new company will have 150 staff at offices in London, Birmingham and Nantwich.

Misys has acquired Crossmar Matching Service, the developer of software for foreign exchange transactions, from Citicorp for £8.3m.

Misys, the financial services software company, has announced plans to set up a £6.5m compliance centre in India next year.

Misys has acquired Eagleye Solutions, the supplier of compliance software to the asset management industry, for up to £15m.

Misys has announced plans for the development of the AssureWeb online transaction system for independent financial advisers, which will include a £9m investment from Norwich Union, Scottish Widows and Friends Provident.

Misys is to shed 150 jobs in its banking software division, including 20 in the UK, and will relocate its online support facility to Manilla.

Misys is to acquire Sunquest, the US healthcare systems supplier, for £287m, in order to expand its Medic Computer Systems subsidiary.

Misys is to acquire DBS Management, the supplier of IT services to the financial adviser sector, for £75m.

Misys is to develop an internet portal for general insurance brokers in partnership with Axa, Groupama Insurances, Royal & Sun Alliance, Allianz Cornhill and Zurich.

Misys is to acquire IE Group, the supplier of software support to independent financial advisers, for £21m.

Misys is to launch a new service that will enable digital TV viewers to buy insurance, in an expansion of its Screentrade internet trading business.

Misys has acquired Financial Options Group for £40m, in order to become a leading supplier of support networks to independent financial advisers.

Misys is selling its Information Systems division to management for £28m.

Misys is to acquire C-ATS Software, the US supplier of risk management software, for $60m.

Helphire has acquired Countrywide Assistance from Misys for £2.2m, in order to expand its legal expense insurance business.

Misys has sold its computer services business to a management team for £10m, in order to focus on software products.

Misys is to acquire Medic Computer Systems, the US medical software company, for £566m, funded partly by a £321m rights issue.

Misys is to acquire Summit Systems, the New York-based financial derivatives trading software company, for £37m.

Misys has acquired Frustum, the US designer of software that enables banks to monitor activities such as foreign exchange trading, for £37m.