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Chiroscience and Celltech are to merge to create a combined biotechnology group valued at £696m, and the new company is expected to make further acquisitions. 16-Jun-1999 Chiroscience has regained the rights for the Chirocaine anaesthetic from Zeneca, in order to clear the way for Zeneca to win approval for its merger with Astra. 02-Mar-1999 Chiroscience has won regulatory approval for its Chirocaine local anaesthetic in Sweden, which is said to be the first time a UK biotechnology company has won a licence for a significant new drug. 17-Dec-1998 Chiroscience is to move into a new £14m facility at Granta Park in Cambridge in early 2000, and it will include offices and laboratories. 12-Oct-1998 Chiroscience claims to have discovered the gene the controls the autoimmune system, which could lead to the development of treatments for a wide range of diseases. 30-Sep-1998 Chiroscience is linking up with Maruishi Pharmaceutical for the development and marketing of its Chirocaine anaesthetic in Japan. 08-Sep-1998 Ascot is acquiring a 30% stake in Chirotech Technology, the Chiroscience subsidiary, for £30m, in order to develop a partnership that can both develop and manufacture compounds for pharmaceutical companies. 11-Aug-1998 Chiroscience has applied to the US FDA for permission to market its Chirocaine local anaesthetic, and a ruling is expected within a year. 30-Apr-1998 Chiroscience has announced a deal in which Zeneca will commercialise its Chirocaine anaesthetic, which should generate at least £200m of additional revenue for Chiroscience. 01-Apr-1998 Chiroscience is setting up a new subsidiary called Rapigene to market its DNA analysis technology, and expects sales of up to £24m within five years. 04-Mar-1998 Chiroscience is linking up with Bristol-Myers Squibb of the US to develop cancer drugs, with BMS contributing to the costs of Chiroscience's technology. 12-Feb-1998 Chiroscience is seeking European approval for Chirocaine, its new anaesthetic. 05-Dec-1997 Chiroscience is in discussions with a number of potential partners for the marketing of Chirocaine, its new local anaesthetic which will be launched next year. 02-Oct-1997 Chiroscience is linking up with Geron of the US to study diseases associated with ageing. 16-Sep-1997 Chiroscience is linking up with Schering-Plough of the US to develop a treatment for asthma at a cost of £23m. 28-Jun-1997 Chiroscience, through its Darwin Discovery subsidiary, is linking up with Hewlett-Packard to develop a new system for DNA analysis. 02-Jun-1997 Chiroscience has announced plans to start clinical trials later this year of a cancer compound that could rival British Biotech's marimastat. 29-Apr-1997 Chiroscience has announced successful trial results for levobupivacaine, a local anaesthetic. 16-Apr-1997 Chiroscience plans to start clinical trials of a potential cancer therapy later this year, which is based on the technology used in British Biotech's Marimastat. 03-Mar-1997 Chiroscience is acquiring Darwin Molecular, the US biotechnology company, for £72m, a move which will give it new skills in genomics and combinatorial chemistry. 21-Nov-1996 Chiroscience is planning 15 new clinical trials on its Levobupivacaine long-lasting local anaesthetic, and is seeking a partner to continue its development. 08-Oct-1996 Chiroscience has launched its first product, an arthritis drug called dexketoprofen, in Spain. 27-Jun-1996 Chiroscience has bought Resolution Chemicals' pilot-scale development centre from E Merck for £5.5m. 08-May-1996 Chiroscience has pulled out of a deal with Pharmacia & Upjohn that was to see them jointly develop Chiroscience's levobupivacaine long-lasting anaesthetic. 26-Apr-1996 Chiroscience has reported good final test results for its levobupivacaine local anaesthetic. 20-Jan-1996 Chiroscience is to partner Medeva in the development of an unspecified product, with therapeutic details to be announced in February. 19-Dec-1995 Chiroscience is discussing technology joint ventures with major generic drug makers as it wants to develop new markets by using its technology to develop new drugs and purify existing ones. 11-Dec-1995 Chiroscience has had its biotech painkiller Dexketoprofen approved in Spain, and other European countries are expected to follow suit. 28-Oct-1995 Chiroscience has made a £77m deal with Pharmacia to jointly develop its anaesthetic, levobupivacaine. 18-Sep-1995
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